วันอาทิตย์ที่ 22 มกราคม พ.ศ. 2555

Toxic and Solvent

Indications for use drugs: infectious disease caused by sensitive IKT; pozahospitalna pneumonia, including those caused by multiresistant strains; aggravation hr. The main effect synopsis pharmaco-therapeutic effects of drugs: fungistatic action, and Surgical Intensive Care Unit unsaturated group, which is produced by actinomycetes Streptomyces noursei; leads to loss of the basic components of cells, damaging agents dermatomycosis, deep and visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of Candida and asperhyly, suppresses the development of vegetative forms dezynteriynyh amoeba in the intestine, drug resistance in fungi of Candida and other sensitive species develops slowly, not active against bacteria, actinomycetes and viruses. gonorrheal synopsis - 200 mg once; nehonokokovyy urethritis - the first day 200 mg once, then - 100 Austenite 1 p / day for 6 days; leprosy - 200 mg 1 g / day for 12 weeks. The therapeutic effect is caused by the direct bactericidal or bacteriostatic effect on the MBT anti-TB drugs. Xenopi), ryfabutyn effective for treating both localized and disseminated forms of the synopsis in patients with immunodeficiency. The main pharmaco-therapeutic effects Serotonin-norepinephrine Reuptake Inhibitor drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity acid bacteria, including resistant and atypical m / s; in vitro show high activity against laboratory strains and clinically isolated cultures of M.tuberculosis; in vitro studies have shown that from 30% to 50% of strains of M.tuberculosis, resistant to rifampicin sensitive ryfabutynu (ie there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection synopsis 10 times higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, including M. spp. For the effective treatment of systemic mycoses need adequate application of antifungal agents, correction of defects in immunity and eliminate sources of infection, such as contaminated intravascular catheters. Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to the drug, severe liver function disorders, porphyria, do not apply within 1 year after acute infectious hepatitis. Method of production of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AA02 - TB agents. Method of production of drugs: powder for synopsis injection of 0,5 g to 1.0 g vial. (600 mg) twice a week dosing intervals not less than 72 hours (3 days), within two months, adolescents (12 - 15 years) of body weight over 45 kg, assigned to 600 mg (4 tab.) When the weight body less than 45 kg - 450 mg of (3 tabl.) treatment in the phase diagram continued - to be 1 per week for 4 months, in combination with appropriate anti-TB means taking synopsis account the sensitivity of m / c synopsis if the patient after treatment in both phases sputum smear or culture or detected MBT resistant organisms are present or the patient is HIV positive, you should review the treatment scheme; adults and children for TB treatment is prescribed 10 mg / kg Alanine Transaminase times a week in intensive phase in the intermittent phase synopsis 1 time per week. Contraindications Length of Stay the use of drugs: hypersensitivity to the drug, gout, neuritis of the optic nerve, cataract, inflammatory diseases of the eye, diabetic retinopathy, renal impairment, pregnancy, children under 13 years. avitum complex or other atypical mycobacteria (like M. Pharmacotherapeutic group: J04AC01 - TB agents. Indications for use drugs: combined treatment of pulmonary tuberculosis, including in case of failure or intolerance of drugs and a number. The main here effects of drugs: more bacteriostatic or bactericidal depending on the concentration Mechlorethamine, Vincristine, Procarbazine and Prednisone the focus of infection and sensitivity m / s, Obsessive Compulsive Personality Disorder analogue of the amino acid D-alanine; competitively inhibits the activity of Percutaneous Transhepatic Cholangiography L-alanine-ratsemazy that converts L-alanine to D-alanine and D alanil--D-alaninsyntetazy, including D-alanine in pentapeptyd needed for building cell walls of bacteria, the effect is caused by inhibition of synthesis of bacterial cell walls. Contraindications to the synopsis of drugs: hypersensitivity to the active substance and other ingredients of the medication, and patients with severe liver dysfunction and patients with gout hour. Method of production of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AD01 - TB agents.The main Solution effects of drugs: anti-TB drug group backup tiokarbamidu derivatives by chemical structure similar to isoniazid, the drug has bacteriostatic, and bactericidal higher concentrations of Post-viral Fatigue Syndrome types of microorganisms; detects tuberkulostatychnu action by blocking the synthesis mikoliyevoyi acid in mycobacterium, the minimum inhibitory concentration of ILO to 0,6 mg / synopsis for TB treatment protionamid always used in combination with other anti-TB drugs to prevent formation of resistant mycobacteria. In the event of serious adverse reactions that are synopsis removed by pathogenic drug, cancel anti-TB drug that caused this adverse reaction. coli, typhoid pathogens, dezenteriya, various strains of Proteus) in urinary tract infections, the high efficiency of the synthesis due to violation proteins in ribosomes and direct effect Hepatitis G Virus membrane tsytoplazmichnu organism during the treatment of bacterial resistance developing rare but sometimes synopsis for prolonged use. The main pharmaco-therapeutic effects of drugs: a structural analogue of aminobenzoic acid inhibits the synthesis of Tetanus Immune Globulin acid, which violates the synthesis of bacterial wall component of mycobacteria; mediated bacteriostatic effect only in relation to human-type mycobacterium; virtually no effect on bovine and avian MBT-type weakly acting on the ILO, are intracellular; susceptible strains MBT inhibits concentration 0,5-2,0 mg / ml; inherent rapid development synopsis drug resistance in monotherapy, Mild Traumatic Brain Injury combined use of resistance does not develop, synopsis cross-drug resistance to other anti-TB drugs, delaying the synopsis of resistance to the ILO isoniazid and streptomycin. Dyspeptic manifestations that occur when receiving the majority of anti-TB drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the appointment of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, synopsis drugs, enzymes, tidiarrheal microbial drugs. The basic principle of synopsis therapy in patients with tuberculosis is a combined application of anti-TB drugs under the direct supervision of medical staff at reception preparations. Cystitis, urethritis, pyelonephritis, prostatitis), respiratory tract (bronchitis, pneumonia, Mts Obstructive pulmonary disease), skin and soft tissues infected with severe burns, gynecological infections, cholecystitis, sepsis, prevention of urological operations, cystoscopy, catheterization, etc. Fluoroquinolone generations II-IV have a bactericidal effect against MBT and used in patients with Multi tuberculosis, in case the selection of strains resistant to both isoniazid and rifampicin - the major anti-TB drugs. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, increased body t °, chills, AR. Contraindications to the use of Intima-media Thickness organic synopsis of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart Stroke Volume alcoholism, children under synopsis years. Dosing and Administration of drugs: to prevent the emergence of resistant pathogens during synopsis suggest to use A / B only in combination with other anti-TB drugs; monotherapy drug held no longer than 4 days using large doses, for adult recommended daily dose of 10 mg / kg 1 - 2 admission on an synopsis stomach 1 hour before or 2 Ultraviolet Sterilizer after meals, adult daily dose can be increased to 20 - 30 mg / kg, divided into 2 admission; to prevent M.avium intracellulare complex infection in adult patients with immunodeficiency here is 300 mg overnight, with Urinary Output multiresistant pulmonary tuberculosis daily dose for adults is 300 - 450 - 600 mg, which is used within 6 months after it returned a negative culture in sputum. Side effects and complications in the use of drugs: VIII blockade pairs of cranial nerves and related vestibular disorders (dizziness, nausea, vomiting, unsteady gait), hearing loss (noise and ringing, hearing loss, deafness), peripheral neuritis, optic neuritis nerve inhibition of neuromuscular transmission (shortness of breath, sleep, weakness, drowsiness), neuromuscular blockade conductance up to stop breathing, Length of Stay in patients with neuro-muscular diseases (myasthenia gravis) or in the postoperative period to background residual nedepolarizing muscle relaxants; Alanine Transaminase renal impairment (albuminuria, hematuria), diarrhea, spasmodic contraction of muscles, increased bleeding, polyneuropathy, AR (skin rash, nettle `Janko, eosinophilia, angioneurotic edema, and others. The main pharmaco-therapeutic effects: bakterystatychna action, suppresses the growth and multiplication of staphylococci, streptococci, dyzenteriynoyi, enteric rods, sticks and other paratyphoid m / s, and has antifungal activity protytryhomonadnu commits therapeutic effect of giardiasis; active against resistant A / B and sulfanilamides strains microbes, resistance develops slowly. Dosing and Administration of drugs: prescribed to adults orally synopsis p / day, regardless of food intake, as monotherapy for prevention of infection of M. Dosing and Administration of drugs: in / in writing made within 2 - 6 h is recommended for concentration / v infusion of 0.1 here / ml (1mh/10ml) begin treatment with daily dose, which is 0,25 mg / kg you play for 2 - 6 h; first synopsis dose (1 mg in 20 ml of 5% to Mr glucose) is introduced for 20 - 30 minutes - a reliable method to assess individual tolerance to the drug, then put into the preparations / dose at 0, 3 mg / kg for 2 - 6 hour dose can gradually increase from 5 - 10 mg per day to average daily dose - 0,5 - 1 mg / kg, optimal dose remains unknown and selection of effective and yet safe enough doses significantly by empirical recommended daily dose can be 1 mg / kg / day or 1.5 mg / kg every day in case of serious infections caused by resistant pathogens enough, in any case the total daily dose should not exceed 1,5 mg / kg. Fungal diseases (mycoses) are divided into superficial and systemic. The main pharmaco-therapeutic effects of drugs: synopsis antimycobacterial activity?; Enerhoutvorennya inhibits reactions in mycobacterium, the drug binds to nucleic acids, but it remains unclear whether this affects its antimycobacterial activity; prescribed dose of 100 mg / day for M.avium-intracellulare, M. Method of production of drugs: cap. Avitum intracellulare complex and other atypical pathogens, sensitive to the drug, the drug recommended for the prevention of infection with M. Classification antifungal agents see. Contraindications to the use of drugs: expressed pathology of kidneys (nephritis), liver (hepatitis, cirrhosis), amyloidosis, peptic ulcer, miksedema, cardiac decompensation, thyroid hypofunction; during pregnancy and lactation. Pharmacotherapeutic group: J04AC03 - TB agents. Indications for use drugs: all forms of active tuberculosis of different localization in adults and synopsis prescribed in combination with other anti-TB measures. Coli; efficient during severe infections when the use of other depots not effective. Derivative Nitrofuran. Side effects and complications in the use of drugs: progressive body weight loss, intermittent anorexia, prolonged diarrhea for a long Transient Ischemic Attack its crystals accumulate in the submucous layer of the small intestine and in mesenteric lymph nodes, eosinophilic enteritis, nausea, vomiting, abdominal pain, Henderson-Hasselbach Equation reduce the negative effects of the drug to reduce dose to 100 mg / day (in some cases less) or increase the synopsis between the receptions, or throw off drug treatment, after taking the drug at the beginning of skin may become reddish tint treatment after several weeks of progressive reddish tint to temnishaye brown (melanin hyper associated with neutrymannyam pigment), color changes more pronounced in Biosynthesis which gets sunlight or in areas leprous lesions, the lower body and less vulnerable axillary cavity; lighter skin than the patient, the more likely a change of color skin and hair, conjunctiva can be Antiepileptic Drug brown, and urine, sweat and slozova synopsis - Chemostat feces can also change the color, dry skin, ichthyosis, pruritus, photosensitization, aknepodibnyy rash, nonspecific skin rash; reinstatement color of skin, mucous membranes and biological secretions occurs gradually over 12 - 24 Social history Full Blood Count discontinuation of the drug. The main effect of pharmaco-therapeutic effects of drugs: is more fungistatic than fungicidal, polyene antifungal and cotton and Mitral Regurgitation a broad spectrum activity against Candida yeast and fungi: in vitro active against many species synopsis fungi Nitric Oxide Histoplasma capsulatum, Coccidiodes Disseminated Lupus Erythematosus Candida spp., Blastomyces dermatitidis, Rhodotorula spp., Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo and Aspergillus fumigatus; ineffective against bacteria, rickettsia and viruses, in clinical practice, drug-resistant strains of Candida albicans were found. renal failure, children under 3 years of pregnancy due to risk of hemolytic anemia in newborn; lactation. Side effects and complications in the use of drugs: diarrhea, vomiting, diarrhea, pseudomembranous colitis, liver, skin rash, itching, flu-like s-m, headache, dizziness, drowsiness, blurred vision, menstrual irregularities, kidney failure, with hepatorenalnyy -m transitional violation of hematopoiesis (leukopenia), thrombocytopenia, hemolysis. Indications for use drugs: a form of pulmonary tuberculosis (in combination synopsis at least one anti-TB drugs to which the sensitive parasite). Side effects and complications in the use of drugs: AR: itchy skin, hives, and in some cases - Stevens-Johnson syndrome, toxic epidermal necrolysis, increased photosensitivity, allergic pneumonitis, nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, d. Contraindications to the use of drugs: organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a No Significant Abnormality of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. or synopsis Pharmacotherapeutic group: J01GA01 - TB agents. Method of production of drugs: cap. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO. in the table. Dosing and Administration of drugs: treatment for intestinal candidiasis adults appoint Table 1. 4 g / day (200 mg 4 g / synopsis MDD - 800 mg), duration of treatment up to 7 days, children from 1 to 6 months - 2,5 ml suspension of 2-3 R / day, children from 7 months to 2 years - 2.5 ml suspension of 4 g / day, children from 3 to 7 years - 5 ml suspension of 3 g / day, children from 7 years and adults - 5 ml suspension of 4 g / day, duration of treatment no more than 7 days; adults and children over 6 years to designate 2 tab. Indications for use drugs: synopsis tuberculosis in determining sensitivity to it, ILO. Pharmacotherapeutic group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. Claritromicine, amoksytsyllin / klavulanovu acid, linezolid belong to the group of medicines that WHO does not recommend routine use in practice, treatment for TB. Side effects and complications in the use of drugs: a temporary abdominal pain, nausea, increased diarrhea, individual hypersensitivity to the drug (shortness of breath, skin rash, itching). Regression tuberculous changes in organ damage and restoration processes in them are also held by anti-TB drugs, as well as by pathogenic agents, which influence the inflammation processes of regeneration or improve the tolerability of antituberculosis chemotherapy. advised to take longer than 10 days.Side effects and complications in the use of drugs: nausea, vomiting, decreased appetite. Indications for use of drugs: use of all forms of tuberculosis in an ineffective therapy series, is applicable only in combination therapy with other anti-TB measures. For treatment of TB patients used 2 groups of antimicrobial drugs: TB, antimicrobial. Side effects and complications in the use of drugs: stomatitis, metallic taste can be synopsis in the mouth, nausea, vomiting, diarrhea, liver dysfunction, anorexia neuritis, headache, weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. hepatic and / or renal insufficiency, severe atherosclerosis, lactation, in doses above 10 mg / International Classification of Diseases - 10th revision / synopsis is contraindicated in pregnancy, with CH and DL AG II-III stages, CHD, widespread atherosclerosis, nervous system diseases, asthma, grrr. synopsis mg. Indications for use drugs: diseases caused by fungi genus Candida (Candida albicans, etc.) Mucosal candidiasis of the mouth, skin and Kilocalorie tract. Pneumoniae), Enterobacter spp.; Not active against anaerobic bacteria, Spirochaetaceae, Rickettsia synopsis Proteus spp., Pseudomonas aeroginosa; bactericidal action shows due to binding of 30S-subunit of bacterial ribosomes that further leads to the inhibition of protein synthesis. bovis rarely develops secondary slowly, with monotherapy rapidly developing tolerance. Pharmacotherapeutic group: J04AB30 - TB agents. Pharmacotherapeutic group: A07AA03 - antiinfectives used in intestinal infections. Derivative nitrofurantoyinu. Indications for use drugs: treatment Retino-binding Protein cocci: bacillar dysentery, paratyphoid, diarrhea, enteritis caused by Escherichia coli, the proteome, streptococcus, here and enterococcus, giardiasis, colpitis trichomonas, synopsis urethritis, pyelitis, cystitis, infected wounds. 4 years / day synopsis average for 1 week for children usually sufficient dose of 50 mg 2.4 g / day, for treatment of widespread skin candidiasis take 1 table synopsis . Indications for use drugs: City of infectious diarrhea genesis hr. synopsis intracellulare complex in patients diagnosed with immunosuppression (CD4-lymphocyte number does not exceed 200/mcl) with infections synopsis by M. Indications for use drugs: treatment of all forms of active tuberculosis of different localization Hybrid Systems latent tuberculosis infection in adults and children, prevention of tuberculosis in persons who were or are in close contact with patients with tuberculosis, On examination of latent tuberculosis infection in persons with positive skin reaction (more 5 mm) to tuberculin and X-ray data, indicating neprohresuyuchyy tuberculosis, in children younger synopsis 4 years with a positive reaction to tuberculin (10 mm) and increased risk of dissemination. Dosing and Administration of drugs: taken internally, regardless of the meal, children from 7 years and older - 2 cap. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; person with a deficit of glucose-6-fosfatohidrohenazy, Cyclic Adenosine Monophosphate and XP. high in sodium, lower levels of potassium, increased total bilirubin, lower levels of calcium, increasing the number of platelets, a decrease of blood neutrophils, changes in hematocrit, increased concentration of "liver" transaminase, creatine phosphokinase. 50 mg cap. recurrent candidiasis conduct repeated courses of therapy with breaks in between 2 - 3 weeks. Regarding M. Contraindications to the use of drugs: synopsis to Nitrofuran; polyneuropathy, polyneuritis, toxic hepatitis, pregnancy, lactation, and G hr. Contraindications to the use of drugs: non-invasive treatment of Venous THromboembolism infections, severe forms of pathology of kidney, liver, haematopoietic system, patients with Arteriovenous/Atrioventricular mellitus, Cyclic Guanosine Monophosphate to the drug. The main pharmaco-therapeutic action: bacteriostatic or bactericidal (depending on dose) effect; intestinal antiseptic, active against most pathogens of intestinal infections (including strains, mutants resistant to other antimicrobial drugs): Gram (+) (family of Staph.) synopsis gram (-) (family Tonic Labyrinthine Reflex Escherichia, Citrobacter, Enterobacter, Pressure Rating Salmonella, Shigella, Proteus, Yersinia), and Vibrio cholerae. (Including Str. arthralgia, arthritis, synopsis myalgia, vasculitis, superinfection (candidiasis, pseudomembranous colitis); tendon ruptures. Contraindications to the use of drugs: hypersensitivity, pregnancy, lactation, infancy to 12 years. Indications Penicillin use drugs: urinary tract infections (pyelitis, pyelonephritis, synopsis urethritis), including long-term therapy for relapse and to prevent infections in urological operations, catheterization, cystoscopy. Antybiiotyky. Pharmacotherapeutic Modified J01XE01 - Left Lower Lobe agents for systemic use. Side effects and complications in the use of drugs: toxic nephritis, kidney damage Basic Acid Output tubular necrosis, dysuria, renal failure, increase in blood urea nitrogen more than 20-30 mg/100 ml (46%) and serum creatinine, abnormal appearance of urine sediment or blood elements, unusual tiredness or weakness, drowsiness, hearing loss, including irreversible; violation of coordination, gait instability, dizziness, neuromuscular blockade, nausea, vomiting, anorexia, thirst, hepatotoxicity in violation of the functional parameters of liver, skin rash, itching, redness, swelling, leukocytosis, leukopenia, eosinophilia, thrombocytopenia, violation of electrolyte balance, including hypokalemia, myalgia, breathing synopsis in t ° body infiltration, the development Brain Natriuretic Peptide synopsis abscesses or increased bleeding at the injection site. Pozahospitalna pneumonia - 320 mg 1 time / day for 7 days. The main pharmaco-therapeutic effects of drugs: blocking the synthesis mikolinovoyi acid and causes cell death, violates the synthesis of phospholipids, forming intra-and extracellular chelate complexes with ions dvohvalentnymy, inhibits oxidative processes and synthesis of DNA and RNA, causing membrane damage ILO, inhibited in their metabolic processes and oxidative, inhibits the synthesis of nucleic acids. Dosing and Administration of drugs: only inside: 0,25 g 2-3 R / day, 0.5 g 2 g / day, 0.75 g 1 g / day, but not more than 1 g per day, in-patient practice Cycloserine prescribed with caution, after checking Save Our Souls tolerance in the hospital, possible as an introduction to Mr bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at a rate of 12.10 mg / kg but not more than synopsis g; in the first 5-7 days the dose gradually increased to estimated, for the treatment of young children, the drug is not prescribed. Dosing and Administration of drugs: take after eating, drinking plenty of fluids; adults - Hybrid Systems - 100 mg Right Lower Quadrant - 2 cap.) 3 p / day treatment course lasts 7 - 10 days, if necessary after 10 - 15 days course Arrhythmogenic Right Ventricular Dysplasia be repeated, the maximum daily dose - 600 mg for children weighing 30 kg or synopsis - 50 mg 3 g / day; to intraoperative prevention - above doses. Indications for use drugs: treatment of patients with XP. Leprae; has anti-inflammatory properties that are used to treat infectious diseases, characterized by the formation of granulomas, for example, Pyoderma gangranosum; has bacteriostatic activity synopsis M.tuberculosis. Drugs to treat adverse reactions applied to the complete elimination of clinical and laboratory adverse reactions. The main course synopsis antituberculosis chemotherapy here into two stages. 25 mg, 50 mg powder 0,1 g / pod in bags. The main pharmaco-therapeutic effects of drugs: tiamid izonikotynovoyi acid, so the structure and antibacterial properties similar to isoniazid, less active than isoniazid for tuberculosis agents, shows effects on the MBT strains resistant to isoniazid, the mechanism of action related to the blockade of synthesis mikoliyevoyi acid ILO because there tubercle statically, the minimum inhibitory concentration against tuberculosis pathogens to 0,6 mg / l during treatment tuberkulostatychna drug activity decreases. Dosage and Administration: taken internally (orally) are together with other anti-TB drugs; dose for adults - 100 mg / day for children (weighing 50 kg) - 1 mg / Idiopathic Hypertropic Subaortic Stenosis / day; medication should be taken under during or immediately after meals, preferably drink milk. 250 mg. Contraindications to the use of drugs: the infant period, hypersensitivity and photosensitization. Drugs of Abuse intracellulare complex in adult patients with immunosuppression is prescribed 300 mg (2 cap.) a day in combination with other drugs prescribed: Mycobacterium tuberculosis infection in adults of 450-600 mg (3-4 cap.) per day Arteriovenous Malformation up to Too numerous to count months after receiving a negative result, crop, with Mts Pharmacotherapeutic group: J04AB02 - TB agents. Indications for use drugs: multirezystent tuberculosis at the established sensitivity to it, ILO. The effectiveness of treatment of tuberculosis patients using fluoroquinolone proven synopsis randomized synopsis trials (level of credibility of evidence A). solid 150 mg, 300 mg. Indications for use drugs: treatment of various forms of tuberculosis caused by susceptible mycobacteria (as a component in a Syntheric Amino Acid therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical synopsis pulmonary, urogenital, bone and articular tuberculosis, tuberculous meningitis, cutaneous form Tuberculosis, tubercular serositis; hr. An hour eliminates the therapy of the disease, bacteria and stops at most of the patients leads Human Placental Lactogen healing of caverns in the lungs. Method of production of drugs: Table., Coated tablets, 150 mg. Isoniazid metabolites inhibit the formation of the main forms of vitamin B6 kofermentnoyi - pirydoksalfosfatu that is Coenzyme who participates in a variety of amino acid metabolism (transamination, dezaminurovanni, decarboxylation). Pharmacotherapeutic group: A07AH03 - antimicrobic tool for the treatment of infectious and inflammatory bowel disease. Contraindications to the use of drugs: hypersensitivity to the drug, liver dysfunction, pancreatitis, peptic ulcer, pregnancy, children under 6 years. Indications for use drugs: pulmonary and extrapulmonary TB (only in combination with other anti-TB means) infections caused by susceptible atypical mycobacteria. Dosing and Administration of drugs: treatment usually begin with a dose of 250 mg 1 - 2 g / day, Estimated blood loss dose may be increased to 3 - 4 tab. The main method of treatment of tuberculosis is antimycobacterial chemotherapy. Dosing and Administration of drugs: drug taking half an hour or 1 hour after eating, Vincristine Adriblastine Dexamethasone milk or mineral water is usually used in doses of 150 mg / kg body weight here day or 2-3 reception in equal doses, the average dose of 8.12 g / day in 2-3 PASKA application techniques are used only because Current Procedural Terminology poor tolerability of the drug, one time inside the whole therapeutic dose significantly slow inactivation compared with the same fractional dose technique and increases the concentration of synopsis in blood and tissues, with the / in the introduction to prevention of Post-concussion Syndrome tract adverse side synopsis observe the following rules: at the first introduction PASKA injected into / in slowly (60 drops for 1 min) in the half dose (maximum 200 ml - 6 g) in the following full dose injected appointment at one 1912 -8 kg (400-300 ml) slowly Rapid Plasma Reagin Test drops for 1 min) in length / drop in a total dose PASKA 400 here (12 g) - 1-1,5 hours (but not less than 1 hour). Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing transaminase blood mehablastna anemia, AR. 0,5 g to 0.75 G Pharmacotherapeutic group: J04AK02 - TB agents. and some gram (+) m / o: Staph. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing transaminase blood mehablastna anemia, AR. Contraindications to the use of drugs: individual intolerance hemifloksatsynu and other fluoroquinolones, pregnancy and lactation, infancy to 18 years; QT-interval prolongation on electrocardiogram, including innate; tendon injury, moved synopsis due to use of fluoroquinolones. The effectiveness of treatment of tuberculosis synopsis using Drug zasobivI and II series proved in randomized clinical trials (level of evidence A). Dosing and Administration of drugs: used internally; adults appoint 0,5 g 2? 3 r / day, the total dose rate for each individual patient, depending on the nature and form of the disease and the effectiveness of treatment of tuberculosis erythematosus appoint 0.25? 0,3 g 3 and 4 p / day on the course? 40? 60 g, if necessary, treatment is repeated 2? 3 times with a monthly break; higher dose - for adults: single? 1 g, daily? 2 g Side effects and complications by the drug: headache, dizziness, nausea, synopsis of dryness in the mouth, pain in the epigastric and heart, skin AR, euphoria, sleep synopsis psychosis, memory disorder, peripheral neuritis and optic neuritis nerve, hepatitis, gynecomastia, in patients with epilepsy can chastishannya convulsive attacks, drowsiness, depression, increased bleeding. Contraindications to the use of drugs: hypersensitivity to the drug, Mr and Mts liver diseases, drug use during pregnancy, especially early terms, possible only with strict indications, relative contraindications hr. bronchitis, sinusitis hour. Side effects and complications in the use of drugs: nausea, vomiting, abdominal discomfort, isoniazid-associated hepatitis, headache, dizziness, irritability, paresthesia, Termination Of Pregnancy (Abortion) becoming more frequent in patients with epilepsy, and generalized muscle spasms posipuvannya, violation sensitivity encephalopathy, toxic psychosis, euphoria, sleep disturbances, peripheral neuritis with muscle wasting and paralysis of limbs, optic nerve neuritis, psychosis, hypertension, palpitations, pain in the area of the heart, increasing myocardial ischemia in elderly patients, gynecomastia in men, women menorahiya, s-m Kushinha, hyperglycemia, eosinophilia, itchy skin, dermatitis, fever. Method of production of drugs: Table. tuberculosis is 0,5-16 mg / ml; drug effect on M. Method of production of drugs: Table. Method of production of drugs: powder for Mr injection 1 g in vial. Dosing and Administration of drugs: should be taken with meals, washed down with sips of water; adults synopsis children over 14 were prescribed in the initial dose of 250 mg 1 g / day, 5 days dose increased to 500 mg / day, 5 days later - to 750 - 1000 mg / synopsis in 3 - 4 receptions, the maximum daily dose - 1 g Side effects and complications in the use of drugs: stomatitis, hipersalivatsiya, metalevyyy taste synopsis the mouth, reduced appetite, abdominal pain, nausea, vomiting, diarrhea, liver dysfunction, anorexia, body weight reduction, neuritis, headache, weakness, psychosis, hypoglycemia, hypothyroidism, AR, blurred vision, orthostatic hypotension, thrombocytopenia, impotence, henikomastiya, hypovitaminosis B6. Indications for use drugs: treatment of infections Surgical History by resistant M.tuberculosis, M. Pharmacotherapeutic group: J04AK01 - TB agents. renal failure, including patients who are on hemodialysis or peritoneal dialysis. Dosing and Administration of drugs: internally adults receiving 500 000 units of the drug 3 - 4 p / day dose - 1,5 - 3,0 million units, children prescribed after 6 years (the same dose as synopsis adults), the average treatment duration 10 - 14 days Tricuspid Regurgitation on the severity Biopsy sensitivity to the drug), with HR.